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Penile Biopsy

PRE-PROCEDURE
INDICATIONS
  • Diagnosis of any abnormal penile lesion that does not have an obvious, benign origin
  • To obtain a diagnosis of lesions that do not respond as expected to medical treatment
  • To obtain a specimen for immunofluorescence testing
CONTRAINDICATIONS
  • Significant coagulopathy
  • Allergy to local anesthetic
  • Partial-thickness biopsies contraindicated if melanoma is suspected
EQUIPMENT
  • Sterile gloves
  • Povidone-iodine or other suitable skin antiseptic (e.g., alcohol, chlorhexidine)
  • Local anesthetic (1-2 mL of 1% lidocaine without epinephrine), syringe with an 18-gauge needle for drawing medicine from the anesthetic vial, and a 27- or 30-gauge needle for injection
  • Specimen container, usually containing formalin
  • Punch biopsy tool (3 mm is usually adequate)
  • Pickups
  • Sharp fine-tissue scissors
  • Suture supplies
ANATOMY

Penis

  • The penile skin overlies the superficial fascia (dartos fascia).
  • Beneath the dartos fascia is the deep fascia (Buck's fascia) of the penis.
  • The neurovascular supply is provided via the dorsal artery and nerve, which lie on the superior aspect of the penis, just lateral to the midline dorsal vein.

PROCEDURE
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  • Links to medical evidence and related procedures

POST-PROCEDURE
COMPLICATIONS
  • Bleeding
  • Infection
  • Possible scarring
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